Dosage ; Usual initial dose: 10mg OD. Initiation of therapy with 5 mg once daily
Combinations ; - see below
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Crestor | AstraZeneca | Radiance Pharmaceuticals Limited | 5mg | 28 | Tablet | per tablet | KES 2,074.00 |
| Crestor | AstraZeneca | Radiance Pharmaceuticals Limited | 10mg | 28 | Tablet | per tablet | KES 2,074.00 |
| Crestor | AstraZeneca | Radiance Pharmaceuticals Limited | 20mg | 28 | Tablet | per tablet | KES 3,143.00 |
| Crestor | AstraZeneca | Radiance Pharmaceuticals Limited | 40mg | 28 | Tablet | per tablet | KES 6,210.00 |
| Rostat | Innocia Life Sciences PVT. Ltd | Pharma Specialities Ltd. | 5mg | 30 | Tablet | per tablet | KES 686.00 |
| Rostat | Innocia Life Sciences PVT. Ltd | Pharma Specialities Ltd. | 10mg | 30 | Tablet | per tablet | KES 1,084.00 |
| Rosucip | Cipla Ltd. | Lords Healthcare Ltd. | 10mg | 30 | Tablet | per tablet | KES 1,092 |
| Rosucip | Cipla Ltd. | Lords Healthcare Ltd. | 20mg | 30 | Tablet | per tablet | KES 1,782 |
| Rosuva | Square Pharmaceuticals Ltd | ACE Pharmaceuticals Ltd | 10mg | 10 | Tablet | per tablet | KES 550.00 |
| RovistaŽ | Getz Pharmaceuticals | Surgipharm Ltd | 5mg | 10 | Tablet | per tablet | KES 301 |
| RovistaŽ | Getz Pharmaceuticals | Surgipharm Ltd | 10mg | 10 | Tablet | per tablet | KES 503 |
| RovistaŽ | Getz Pharmaceuticals | Surgipharm Ltd | 20mg | 10 | Tablet | per tablet | KES 744 |
| Rozar | Prism Life Sciences | Galaxy Pharmaceuticals Ltd | 5mg | 30 | Tablet | per tablet | KES 650.00 |
| Rozar | Prism Life Sciences | Galaxy Pharmaceuticals Ltd | 10mg | 30 | Tablet | per tablet | KES 1,080.00 |
| Rozar | Prism Life Sciences | Galaxy Pharmaceuticals Ltd | 20mg | 30 | Tablet | per tablet | KES 1,680.00 |
| Rozavel | Sunlight International Trading (Africa) Co., Ltd | Harley's Limited | 5mg | 30 | Tablet | per tablet | KES 900 |
| Rozavel | Sunlight International Trading (Africa) Co., Ltd | Harley's Limited | 10mg | 30 | Tablet | per tablet | KES 1,400 |
| X-plended | Laborate | Harley's Limited | 5mg | 10 | Tablet | per tablet | KES 300.00 |
| X-plended | Laborate | Harley's Limited | 10mg | 10 | Tablet | per tablet | KES 477.00 |
| Crestat | CCL Pharma | Harley's Limited | 5mg | 10 | Tablet | per tablet | KES 285.00 |
| Crestat | CCL Pharma | Harley's Limited | 10mg | 10 | Tablet | per tablet | KES 459.00 |
| Crestat | CCL Pharma | Harley's Limited | 20mg | 10 | Tablet | per tablet | KES 764.00 |
| Robestar | Sandoz | Laborex Kenya Eurapharma Ltd | 10mg | 30 | Tablet | per tablet | KES 1,248.00 |
| Robestar | Sandoz | Laborex Kenya Eurapharma Ltd | 20mg | 30 | Tablet | per tablet | KES 1,510.00 |
| Rosucor | Torrent Pharmaceuticals Ltd. | Medox Pharmaceuticals Ltd. | 10mg | 30 | Tablet | per tablet | KES 1,150.00 |
| Rosugard | Cipla Ltd. | Surgipharm Ltd | 10mg | 30 | Tablet | per tablet | KES 1,150.00 |
| Rosugard | Cipla Ltd. | Surgipharm Ltd | 20mg | 30 | Tablet | per tablet | KES 1,860.00 |
| Rovas | Intas Pharmaceuticals Ltd | Medisel Kenya Ltd | 5mg | 30 | Tablet | per tablet | KES 650.00 |
| Rovas | Intas Pharmaceuticals Ltd | Medisel Kenya Ltd | 10mg | 30 | Tablet | per tablet | KES 1,035.00 |
| Rovas | Intas Pharmaceuticals Ltd | Medisel Kenya Ltd | 20mg | 30 | Tablet | per tablet | KES 1,750.00 |
| Rovista | Getz Pharmaceuticals | Surgipharm Ltd | 5mg | 10 | Tablet | per tablet | KES 322.00 |
| Rovista | Getz Pharmaceuticals | Surgipharm Ltd | 10mg | 10 | Tablet | per tablet | KES 539.00 |
| Rovista | Getz Pharmaceuticals | Surgipharm Ltd | 20mg | 10 | Tablet | per tablet | KES 796.00 |
| Rozavel | Sun Pharmaceuticals Ltd | Sunpar Pharmaceuticals Ltd. | 5mg | 30 | Tablet | per tablet | KES 1,100.00 |
| Rozavel | Sun Pharmaceuticals Ltd | Sunpar Pharmaceuticals Ltd. | 10mg | 30 | Tablet | per tablet | KES 1,550.00 |
| X-Plended | Pharmevo Pharmaceuticals Ltd | Harley's Limited | 5mg | 10 | Tablet | per tablet | KES 385.00 |
| X-Plended | Pharmevo Pharmaceuticals Ltd | Harley's Limited | 10mg | 10 | Tablet | per tablet | KES 612.00 |
| X-Plended | Pharmevo Pharmaceuticals Ltd | Harley's Limited | 20mg | 10 | Tablet | per tablet | KES 606.00 |
| Zyrova | Zydus Cadila Healthcare | Harley's Limited | 5mg | 30 | Tablet | per tablet | KES 960.00 |
| Zyrova | Zydus Cadila Healthcare | Harley's Limited | 10mg | 30 | Tablet | per tablet | KES 1,100.00 |
| Rosuvastatin | |
|---|---|
| Mode Of Action | 3-hydroxy-3 methylglutaryl co-enzyme A (HMG-COA) reductase - the enzyme inhibitor which catalyses the early rate limiting step in cholesterol biosynthesis-conversion of HMG-Co A to mevalonate. |
| Drug Indication | Adjuvant to diet in primary hypercholestrolaemia; homozygous familial hypercholesterolemia. |
| Precautions | Monitor liver functions; heavy alcoholics; rhabdomyolysis. |
| Contra-Indications | Active liver disease or unexplained persistent defects in liver function tests; pregnancy and lactation; hypersensitivity to rovustatin. |
| Side Effects | GI disturbances, headache, dizziness, insomnia, myalgia, asthenia, hypertonia, paresthesia, rash and pruritis. |
| Dosage | Usual initial dose: 10mg OD. Initiation of therapy with 5 mg once daily should be considered for patients requiring less aggressive LDL-C reductions. Dose adjustments to the next dose level can be made after 4 weeks. |
| Pregnancy Category | Category X |
| Pregnancy Category Description | Drugs that have such a high risk of causing permanent damage to the foetus that they should be avoided in pregnancy or when there is possibility of pregnancy. |
| Drug Category | DRUGS ACTI NG ON THE CARDIO-VASCULAR SYSTEM |
| Drug Sub-Category | Statins |